PAINE #PANCE Pearl – Musculoskeletal Posted by Kristopher Maday PA-C 0 Last week we polled everyone and the results are: Answer Anti-dsDNA is the MOST SPECIFIC for SLE when positive, but ANA is MOST SENSITIVE. This is why ANA is the antibody is used for screening and anti-dsDNA is used for confirming. Share this: Share on X (Opens in new window) X Share on Facebook (Opens in new window) Facebook Like Loading... Related