Infectious Disease Answer

 

Diagnosis: Acute rheumatic fever

Criteria: Jones criteria

 

Acute rheumatic fever (ARF) is a sequella of symptoms that typically occur 2-4 weeks after an untreated bout of group A Streptoccocal (GAS) pharyngitis.  Symptoms include arthritis, carditis, erythema marginatum, CNS symptoms, and subcutaneous nodules.

 

Jones criteria is constellation of symptoms of ARF and are subdivided into major and minor manifestations.

 

Major

Carditis

Arthritis

CNS involvement

Subcutaneous nodules

Erythema marginatum

Minor

Arthralgia

Fever

Elevated acute phase reactants

Prolonged PR interval

 

The diagnosis of ARF is made using the Jones criteria and is positive if the patient has evidence of a preceding GAS infection and:

  • Two major manifestations

or

  • One major and two minor manifestations

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