Infectious Disease Answer


Diagnosis: Acute rheumatic fever

Criteria: Jones criteria


Acute rheumatic fever (ARF) is a sequella of symptoms that typically occur 2-4 weeks after an untreated bout of group A Streptoccocal (GAS) pharyngitis.  Symptoms include arthritis, carditis, erythema marginatum, CNS symptoms, and subcutaneous nodules.


Jones criteria is constellation of symptoms of ARF and are subdivided into major and minor manifestations.





CNS involvement

Subcutaneous nodules

Erythema marginatum




Elevated acute phase reactants

Prolonged PR interval


The diagnosis of ARF is made using the Jones criteria and is positive if the patient has evidence of a preceding GAS infection and:

  • Two major manifestations


  • One major and two minor manifestations

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