32yo, G2P2002, who presents to your practice for her annual well-woman examination.  She has recently moved and is establishing care.  She can’t recall the last time she had a pap smear performed, but is “pretty sure” it was more than 3 years ago.  She does not smoke, has no significant FH for GYN malignancies (cervical/ovarian/breast), and is otherwise healthy.  Pap smear performed in the office was cytology negative, but HPV positive.




For women ≥ 30 years of age with a cytology (-), but HPV (+) pap, you really have two options depending on your access to testing:

  1. If you can perform HPV DNA typing, then:
    1. Repeat cotesting in 1 year if HPV 16/18 (-)
    2. Proceed with colposcopy if HPV 16/18 (+)
  2. If you don’t have access to DNA typing, then
    1. Repeat cotesting in 1 year



  1. 2013 ASCCP Guidelines –

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