Question #1

Which of the following genetic mutations is seen with chronic myelogenous leukemia?

Answer:

Translocation of chromosome 9 and 22.  This new chromosome 22 is called “Philadelphia chromosome” after the city where the two hospitals that first identified the gene mutation in 1960 were both located.

http://www.cancer.gov/types/leukemia/patient/cml-treatment-pdq

Question #2

Which of the following cancer markers are classically associated with ovarian cancer?

Answer:

CA-125