PAINE #PANCE Pearl – Pediatric Edition



What are the six (6) classic infectious exanthems of childhood and what organism causes each?




The chart below lists the classic exanthems of childhood, the organism that causes, and the “number” disease that were given to them in 1905.


It should be noted that Duke’s Disease (fourth disease) is not widely accepted as a true infectious exathem.


  1. Bialecki C, Feder HM, Grant-Kels JM. The six classic childhood exanthems: a review and update.. Journal of the American Academy of Dermatology. 1989; 21(5 Pt 1):891-903. [pubmed]
  2. Drago F, Ciccarese G, Gasparini G. Contemporary infectious exanthems: an update.. Future Microbiology. 2017; 12:171-193. [pubmed]

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