Hampton’s Hump


Other Known Aliasesnone


Definitionwedge-shaped opacity in the periphery of the lung on chest radiography usually with its base along the pleural margins.


Clinical SignificanceOccurs as a result of infarction and subsequent hemorrhage from the bronchial arteries classically due to a pulmonary embolism, but can also be from anything that causes infarction of lung parenchyma.  The sensitivity and specificity of this finding is not robust and is, by definition, a late finding that is really no longer seen in modern medicine.


History – Named after Aubrey Otis Hampton (1900-1955), an American radiologist who received his medical degree from Baylor University in 1925.  He rose through the ranks quickly in the field of radiology ultimately taking a position as chief of radiology at Massachussetts General in 1941.  He first described his eponymous finding in 1940 in his manuscript entitled “Correlation of postmortem chest teleroentgenograms with autopsy findings”.

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  5. Up To Date. www.uptodate.com
  6. Radiopaedia. Hamptons’ Hump. https://radiopaedia.org/articles/hampton-hump-2
  7. Schatzki R, Lingley JR. Aubrey O. Hampton, 1900-1955. The American journal of roentgenology, radium therapy, and nuclear medicine. 1956; 75(2):396-7. [pubmed]
  8. Ladeiras-Lopes R, Neto A, Costa C, et al. Hampton’s hump and Palla’s sign in pulmonary embolism. Circulation. 2013; 127(18):1914-5. [pubmed]
  9. Hampton AO, Castleman B.  Correlation of postmortem chest teleroentogenograms with autopsy findings.  Am J Roentgenol Radium Ther. 1940;34:305-326.

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