Other Known Aliases – none
Definition – an acquired, localized fibrotic disorder of the tunica albuginea where thick, fibrous plaques compress the corpora cavernosa
Clinical Significance – The pathogenesis of Peyronie’s disease is unknown and is postulated to be multifactorial. Patients experience pain, penile deformity, and sexual dysfunction
History – Named after François de la Peyronie (1678-1747), who was a French surgeon and received his medical training as a barber-surgeon in Montpellier in 1695. He continued his academic career teaching and practicing surgery and anatomy throughout France. In 1736, he was appointed first-surgeon to King Louis XV and was instrumental in organizing formal training in the surgical arts and was a major force in the creation of the 1743 law that banned barbers from practicing surgery. Also in 1743, he first described the eponymous disease in a book on ejaculation dysfunction where described “indurations of the cavernous bodies like rosary beads” leading to penile curvature. His last name, lapeyronie, means litter stone because his father was a stone cutter. Its a shame he didn’t pursue management of kidney stones as his claim to fame.
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Fischer LP, Ferrandis JJ, Blatteau JE. [François de Lapeyronie, from Montpellier (1678-1747). “Surgery restorer” and universal spirit. The soul, Musc, rooster eggs]. Histoire des sciences medicales. ; 43(3):241-8. [pubmed]