Whipple Operation


Other Known AliasesKausch-Whipple procedure

DefinitionRadical pancreaticoduodenectomy with distal antrectomy, cholestectomy, and pancreaticojejunostomy, choledocojejunostomy, and gastrojejunostomy

Clinical Significance Used for resection of carcinoma of the head of the pancreas.

History – The first resection of a periampullary cancer was performed by German surgeon Walther Kausch (1867-1928) in 1909, took four hours to complete, and the patient survived for 9 months.  American surgeon Allen Oldfather Whipple (1881-1963) began working on and refining the procedure in 1935 and in 1940, successfully shortened it to a one-stage procedure.


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  5. Whipple AO. Observations on radical surgery for lesions of the pancreas. Surgery, gynecology & obstetrics. 1946; 82:623-31. [pubmed]

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